Pulmatrix Highlights Recent Report Predicting Rapid Growth for Inhaled Drug Delivery Methods
Recent white paper by Envigo explains the advantages of delivering drugs to the lungs--and describes how this delivery method is increasingly being used for a wide variety of diseases
LEXINGTON, Mass., Sept. 23, 2016 /PRNewswire/ -- Pulmatrix, Inc. (NASDAQ: PULM) today announced that a recent white paper, What is the future of inhalation delivery?, by global research and consulting firm Envigo predicts rapid growth for drugs that are delivered to the lungs through inhalation. "The global market for inhalation drug delivery methodology alone is expected to reach US $48bn by 2016," says the report.
Why is inhaled drug delivery so promising? "As the white paper describes, inhaling drugs into the lungs has important advantages over taking pills," says David Edwards, Gordon McKay Professor in the School of Engineering and Applied Sciences at Harvard University and founder of Advanced Inhalation Research. "It allows drugs to be delivered that can't be taken orally. It allows lower doses compared to pills, reducing side effects. And it usually gets drugs into the body faster than taking a pill."
Until recently, the major use of inhaled drugs has been for asthma and chronic obstructive pulmonary disease (COPD), Envigo reports. That use continues to grow rapidly, as the incidence of those diseases increases. "It has been estimated that by 2030, COPD will be the 4th leading cause of death worldwide," the report says. Pulmatrix is targeting this market with its inhaled drug for COPD, PUR0200, being developed in collaboration with Mylan.
But delivering drugs to the lungs is "increasingly being investigated" for a wide variety of other diseases as well, the report says. Analysts at Envigo found 1350 studies over the last four years that targeted 802 different diseases with inhaled drugs. Helping to drive this explosive growth has been "recent advances in the manufacture of dry powder and liquid formulations" to deliver inhaled drugs, the white paper says.
For example, Pulmatrix's own iSPERSE dry powder technology uses particles that 'fly' easily to deliver drugs. "Our technology can deliver virtually any type of drug to the lungs, even in patients who have trouble breathing in," explains Pulmatrix's Chief Scientific Officer, David L. Hava, PhD.
In particular, both the Envigo white paper and Pulmatrix see cystic fibrosis as a major growth area for inhaled drugs. "For instance, Pulmatrix's PUR1900 drug candidate, which combines an existing antifungal drug with the company's dry powder technology, is making it possible to directly treat fungal infections in the lungs of cystic fibrosis patients," says Stanford University CF expert Richard Moss M.D. "That could offer major benefits to CF patients."
Once seen as a "niche delivery methodology," delivering drugs through inhalation has the potential to become much more widely used, thanks to recent advances, the Envigo report concludes.
SOURCE Pulmatrix, Inc.