Press Releases

Pulmatrix enters into merger agreement

Santa Rosa, Ca., March --- March 16, 2015 – Ruthigen, Inc.   (NASDAQ: RTGN) (“Ruthigen”), and Pulmatrix, Inc., (“Pulmatrix”), a Lexington, Massachusetts based clinical stage biotechnology company, announced today that they have entered into a definitive merger agreement. Upon satisfaction of the closing conditions contained in the merger agreement, Pulmatrix will become a wholly-owned subsidiary of Ruthigen and all of Pulmatrix’s debt and equity securities outstanding prior to the consummation of the merger will be exchanged for shares of Ruthigen common stock that will represent approximately 81% of the outstanding common stock of Ruthigen. In connection with Pulmatrix’s entry into the merger agreement, certain existing institutional investors in Pulmatrix entered into stock purchase agreements with Pulmatrix to invest an additional $10,000,000 in Pulmatrix upon the closing of the merger. Pulmatrix also raised approximately $4,500,000 in February 2015, in contemplation of entering into the merger agreement.

Upon completion of the merger, Ruthigen will be renamed Pulmatrix, Inc. and, pending NASDAQ approval of Pulmatrix’s initial listing application in connection with the merger, the surviving  company’s  common  stock  will  continue  to  trade  on  The  NASDAQ  Capital Market after the merger. It is anticipated that the combined company will focus its resources and efforts on the development of Pulmatrix’s next-generation inhaled therapeutic products.

Upon  completion of  the  merger,  Dr.  Robert  Clarke,  President  and  Chief  Executive Officer of Pulmatrix, will be appointed as the President and Chief Executive Officer of the combined company and the combined company will be headquartered in Lexington, Massachusetts.  Prior to joining Pulmatrix in 2004, Dr. Clarke was a Director of Life Sciences at Alkermes, Inc. (NASDAQ: ALKS).

"A merger with Ruthigen provides a strong financial foundation with enhanced access to capital to further Pulmatrix's mission of innovative inhaled product development for patients with significant unmet needs in respiratory disease," Dr. Clarke said. "This transaction represents an excellent opportunity to advance our novel iSPERSE inhaled dry powder platform and lead CF candidate into clinical development and to meet our long-term growth objective of building a leading company around a robust pipeline for respiratory disease."

Terry McGuire, senior Pulmatrix board member and founding partner at Polaris Partners, Pulmatrix’s largest shareholder, noted, “This transaction provides significant momentum for Pulmatrix to achieve its goals in the next stage of its development.”  Mr. McGuire co-founded several  companies including Inspire  Pharmaceuticals which  was  acquired by  Merck  &  Co (MRK) in 2011 and Advanced Inhalation Research, Inc. which was acquired by Alkermes, Inc. (NASDAQ: ALKS) in 1999. He also represented Polaris on the board of numerous life science companies including Decode Genetics, which was acquired by Amgen (AMGN); Transform Pharmaceuticals, which was acquired by Johnson & Johnson (JNJ); and Cubist Pharmaceuticals, which was acquired by Merck & Co.

Dr. Scott Rocklage, the former Chairman & CEO of Cubist Pharmaceuticals, also serves on the board of Pulmatrix.  He is currently a managing partner at 5AM Ventures, another lead investor in Pulmatrix. Dr. Rocklage commented, “The Pulmatrix Board sees significant opportunities for growth based on the company’s novel product pipeline built upon the unique iSPERSE technology.” 5AM Ventures was a founding investor in Pearl Therapeutics which was acquired by AstraZeneca (NYSE: AZN) in 2013.

Hoji Alimi, CEO and Chairman of Ruthigen, said, "This merger has the potential to provides a significant business growth opportunity for our combined companies.  We anticipate that the introduction of a new team of scientists and management with a proven track record, as well as Pulmatrix’s new drug development programs, will catalyze significant growth opportunities in the near future.”

The merger, which has already been approved by the Boards of Directors of both companies, is subject to certain conditions, including NASDAQ approval of an initial listing of the merged entity's common stock on NASDAQ on a post-merger basis, approval of the merger by stockholders of Ruthigen and Pulmatrix, and other customary closing conditions.

Palladium Capital Advisors, LLC is serving as the placement agent and financial advisor to Pulmatrix. Dawson James Securities, Inc. acted as an advisor to Ruthigen.

This communication is being made with respect to the proposed merger transaction involving Ruthigen and Pulmatrix. Ruthigen will file with the SEC a current report on Form 8-K, which includes the merger agreement. In addition, Ruthigen will file a preliminary proxy statement with the SEC and a registration statement on Form S-4 in connection with the issuance of shares of Ruthigen common stock in the merger of which such proxy statement will form a part in connection with the transaction and will mail the final proxy statement to Ruthigen stockholders of record at the record date for the special meeting of the stockholders to be held to provide requisite stockholder approvals relating to the proposed transaction. The proxy statement contains information about Ruthigen, Pulmatrix, the proposed merger, and related matters. STOCKHOLDERS ARE URGED TO READ THE PROXY STATEMENT CAREFULLY WHEN IT IS AVAILABLE, AS IT WILL CONTAIN IMPORTANT INFORMATION THAT STOCKHOLDERS SHOULD CONSIDER BEFORE MAKING A DECISION ABOUT THE MERGER. In addition to receiving the proxy statement and proxy card by mail, Ruthigen stockholders will also be able to obtain the proxy statement, as well as other filings containing information about Ruthigen, without charge, from the SEC's web site ( or, without charge, by contacting Sameer Harish at (707) 525-9900. This announcement is neither a solicitation of proxy, an offer to purchase, nor a solicitation of an offer to sell shares of Ruthigen. Ruthigen and its executive officers and directors may be deemed to be participants in the solicitation of proxies from Ruthigen’s stockholders with respect to the matters relating to the proposed merger. Pulmatrix may also be deemed a participant in such solicitation. Information about Ruthigen’s executive officers and directors is available in Ruthigen’s Annual Report on Form 10-K/A for the year ended March 31, 2014 filed with the SEC on July 23, 2014. Information regarding any interest that Pulmatrix or any of the executive officers or directors of Pulmatrix may have in the transaction with Ruthigen will be set forth in the proxy statement when it becomes available.

This  announcement  is  neither  a  solicitation  of  proxy,  an  offer  to  purchase,  nor  a solicitation of an offer to sell shares of Ruthigen.

About Pulmatrix

Pulmatrix is a clinical stage biotechnology company advancing a new generation of inhaled therapeutics in a novel dry powder delivery platform. The platform, called iSPERSE (inhaled small particles easily respirable and emitted), represents a new paradigm in inhaled drug delivery using particle engineering to create dry powders with unique properties: aerodynamically small, dense particles with highly efficient dispersibility and delivery to the airways. The iSPERSE powders can be used with an array of dry powder inhaler technologies and can be formulated with  virtually  any  drug  substance.   Pulmatrix  is  rapidly  advancing  a  pipeline  of  products including PUR0200, a once daily inhaled bronchodilator for chronic obstructive pulmonary disease and PUR1900, an inhaled anti-infective for the treatment of cystic fibrosis.  Both PUR0200 and PUR1900 are developed using Pulmatrix’s iSPERSE technology.

About Ruthigen

Ruthigen is a biopharmaceutical company focused on the discovery, development and commercialization of novel therapeutics designed to prevent and treat infection in invasive applications. The company’s lead drug candidate, RUT58-60, is a broad-spectrum anti-infective that Ruthigen is developing for the prevention and treatment of infection in surgical and trauma procedures. For more information, visit

Forward-Looking Statement Disclosure

This press release contains certain "forward-looking statements'' within the meaning of the  Private  Securities  Litigation  Reform  Act  of  1995,  as  amended,  including  statements regarding the efficacy of potential products, the timelines for bringing such products to market, and the availability of funding sources for continued development of such products. Forward- looking statements are based on management's estimates, assumptions, and projections, and are subject to uncertainties, many of which are beyond the control of Ruthigen and/or Pulmatrix. Actual results may differ materially from those anticipated in any forward-looking statement. Factors that may cause such differences include the risks that (a) there may be regulatory or litigation obstacles to completing the merger, or stockholders of Ruthigen  may not approve the merger, (b) The NASDAQ Capital Market may not accept the shares of the merged company for listing, (c) potential products that appear promising to Pulmatrix cannot be shown to be efficacious or safe in subsequent preclinical or clinical trials, (d) Pulmatrix will not obtain appropriate or necessary governmental approvals to market these or other potential products, (e) Pulmatrix may not be able to obtain anticipated funding for their development projects or other needed funding, and (f) Pulmatrix may not be able to secure or enforce adequate legal protection, including patent protection, for their products.

Sameer Harish, CFO – (707) 525-9900

Robert Clarke, Ph.D., CEO - (781) 357-2333

Media Contacts:
Sameer Harish, CFO – (707) 525-9900 or

Kevin O’Driscoll – Director of Business Development - (781)-357-2361 or